Prediction Pumas UNAM vs Guadalajara 2025/2026 season – Betting Tips for the Liga MX on 06/10/2025

Match context

This clash at the Estadio Olímpico de Universitario promises to be a heated Liga MX encounter as Pumas UNAM welcome Guadalajara on October 6, 2025. The stage is set in Mexico City under referee Daniel Quintero Huittrón, and the duel carries significance with both teams hovering around mid-table in Apertura round 12; Guadalajara sit narrowly above Pumas in ninth while the hosts occupy tenth. Recent form paints a picture of inconsistency from both sides, but there are clear narratives that tilt the balance and point toward an entertaining game for neutrals.

Form and key statistics

Pumas arrive off a mixed run, including a heavy 4-1 reverse to América in their most recent fixture where veteran goalkeeper Keylor Navas was still noted as the best performer for his side. The overall league picture for Pumas shows three wins, four draws and four losses across eleven games, with 14 goals scored and 17 conceded. At home their defensive numbers look steadier — concede fewer at the Olímpico — and that home setting with a 72,000 capacity is always a factor for the university side.

Guadalajara, meanwhile, bring sharper attacking metrics to the table. They have produced more shots, more shots on target and a higher over-2.5 goals percentage than Pumas so far this season, and their last outing ended in a 2-0 victory over Puebla with Omar Nicolás Govea García standing out. Guadalajara’s campaign has been equally up and down: four wins, two draws and five defeats, 16 goals for and 17 against. Their recent head-to-head advantage is another talking point: they claimed the last meeting earlier this year on March 2.

Both teams register similar goal tallies and defensive frailties across the campaign, which suggests space will open up and scoring chances will be available. Statistical trends underline Guadalajara’s ability to produce games featuring multiple goals, while Pumas at the Olímpico tend to be more resolute but are still vulnerable when opponents press high and create sustained pressure.

Prediction and betting tip

Expect an open, end-to-end encounter where Guadalajara’s attacking intent will meet Pumas’ home resilience. The momentum shown by Guadalajara in attack and the recent heavy defeats and wins for Pumas point toward a fixture that will produce goals rather than a dour stalemate. With both sides combining for a healthy number of goals this season and Guadalajara’s higher over-2.5 percentage, the data suggests value on the goals market.

Betting suggestion: Back Over 2.5 goals.