NFL Week 10 Picks From the MMQB Staff: Eagles Visit Packers on Monday Night

Midseason Week 10 shows clear consensus on several favorites (Broncos, Colts, Bears, Bills, Seahawks, Lions), while prime-time clashes — Steelers at Chargers, Eagles at Packers, Rams at 49ers — feature splits. For bettors: back the unanimous panel picks for safer straight-up wagers, but be cautious on 4-3 and 5-2 splits (Patriots-Buccaneers, Steelers-Chargers, Ravens-Vikings, Jaguars-Texans) where injury news and momentum could swing spreads.

Week 10 overview: trade deadline done, stakes rising

The trade deadline has passed and the season sits at its midpoint. A week of games carries meaningful playoff implications, with several unanimous panel picks and a handful of tight splits that deserve close attention from bettors and fantasy managers alike.

Raiders at Broncos

• Albert Breer: Broncos

• Clare Brennan: Broncos

• Mitch Goldich: Broncos

• Gilberto Manzano: Broncos

• Conor Orr: Broncos

• John Pluym: Broncos

• Matt Verderame: Broncos

Falcons vs. Colts (in Berlin)

• Albert Breer: Colts

• Clare Brennan: Colts

• Mitch Goldich: Colts

• Gilberto Manzano: Colts

• Conor Orr: Colts

• John Pluym: Colts

• Matt Verderame: Colts

Giants at Bears

• Albert Breer: Bears

• Clare Brennan: Bears

• Mitch Goldich: Bears

• Gilberto Manzano: Bears

• Conor Orr: Bears

• John Pluym: Bears

• Matt Verderame: Bears

Bills at Dolphins

• Albert Breer: Bills

• Clare Brennan: Bills

• Mitch Goldich: Bills

• Gilberto Manzano: Bills

• Conor Orr: Bills

• John Pluym: Bills

• Matt Verderame: Bills

Ravens at Vikings

• Albert Breer: Ravens

• Clare Brennan: Vikings

• Mitch Goldich: Ravens

• Gilberto Manzano: Ravens

• Conor Orr: Ravens

• John Pluym: Vikings

• Matt Verderame: Ravens

Browns at Jets

• Albert Breer: Jets

• Clare Brennan: Jets

• Mitch Goldich: Jets

• Gilberto Manzano: Jets

• Conor Orr: Browns

• John Pluym: Jets

• Matt Verderame: Jets

Patriots at Buccaneers

• Albert Breer: Buccaneers

• Clare Brennan: Patriots

• Mitch Goldich: Buccaneers

• Gilberto Manzano: Patriots

• Conor Orr: Buccaneers

• John Pluym: Patriots

• Matt Verderame: Buccaneers

Saints at Panthers

• Albert Breer: Panthers

• Clare Brennan: Panthers

• Mitch Goldich: Panthers

• Gilberto Manzano: Panthers

• Conor Orr: Saints

• John Pluym: Panthers

• Matt Verderame: Panthers

Jaguars at Texans

• Albert Breer: Texans

• Clare Brennan: Jaguars

• Mitch Goldich: Jaguars

• Gilberto Manzano: Jaguars

• Conor Orr: Jaguars

• John Pluym: Jaguars

• Matt Verderame: Texans

Cardinals at Seahawks

• Albert Breer: Seahawks

• Clare Brennan: Seahawks

• Mitch Goldich: Seahawks

• Gilberto Manzano: Seahawks

• Conor Orr: Seahawks

• John Pluym: Seahawks

• Matt Verderame: Seahawks

Rams at 49ers

• Albert Breer: Rams

• Clare Brennan: Rams

• Mitch Goldich: Rams

• Gilberto Manzano: Rams

• Conor Orr: Rams

• John Pluym: 49ers

• Matt Verderame: Rams

Lions at Commanders

• Albert Breer: Lions

• Clare Brennan: Lions

• Mitch Goldich: Lions

• Gilberto Manzano: Lions

• Conor Orr: Lions

• John Pluym: Lions

• Matt Verderame: Lions

Steelers at Chargers

• Albert Breer: Steelers

• Clare Brennan: Steelers

• Mitch Goldich: Steelers

• Gilberto Manzano: Chargers

• Conor Orr: Chargers

• John Pluym: Chargers

• Matt Verderame: Steelers

Eagles at Packers

• Albert Breer: Eagles

• Clare Brennan: Eagles

• Mitch Goldich: Eagles

• Gilberto Manzano: Eagles

• Conor Orr: Eagles

• John Pluym: Eagles

• Matt Verderame: Packers

Guide to every NFL team's trade deadline: Candidates to be moved, targets who could fit, biggest needs

Betting takeaways

Back panel consensus favorites for lower-variance straight-up plays (unanimous or near-unanimous). On 4-3 and 5-2 splits, treat wagers as higher risk — shop the spread, monitor injury reports (notably the Texans’ quarterback status), and consider player props or teasers if you want exposure while limiting downside. Prime-time games with narrow panel margins are the most likely to move markets; smallest edges can be decisive.

Our writers and editors pick winners in all 14 games, including a few between top contenders.

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